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Another kind of study is to conduct a prospective cohort study, looking at differences in HIV incidence between two groups of people according to their usage of condoms.This cannot be a randomised controlled study, but participants’ HIV and STI incidence can be related to their condom use either at baseline or preferably (because behaviours change over time) by means of regular questionnaires and monitoring.The efficacy of an intervention is how well it works in a scientific trial or when people use it as indicated, i.e.

While condoms offer useful and vital protection, they have also become associated with promiscuity and infidelity.In one of the most highly publicised statements, in October 2003, the President of the Vatican's Pontifical Council for the Family, Cardinal Alfonso Lopez Trujillo, said: "The AIDS virus is roughly 450 times smaller than the spermatozoon.The spermatozoon can easily pass through the 'net' that is formed by the condom.Another is that the HIV-positive partner will be chronically infected and so will not have the very high viral load characteristic of acute HIV infection.Thirdly, in long-term serodiscordant relationships, studies have shown that the HIV-negative partner can acquire a degree of immunity to their partner’s HIV.

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